Key Takeaways
- FDA Leadership Shakeup: Commissioner Marty Makary resigns amid internal friction, leaving the dietary supplement industry watching closely for future regulatory direction.
- Major Industry Consolidation: Unilever acquires greens supplement brand Grüns for a reported $1.2 billion, signaling continued investment in premium wellness.
- Focus on Precision Supplementation: The 2026 U.S. News OTC Report highlights a shift toward targeted, life-stage-focused wellness, with new categories like collagen peptides and menopause support.
- Retail Expansion for Digital Brands: AG1 debuts at Ulta Beauty and BODi enters brick-and-mortar retail, showing a strong push for omnichannel presence.
Top Stories
FDA Commissioner Resigns Amid Internal Friction
FDA Commissioner Marty Makary has abruptly resigned from the agency amid reports of internal friction regarding the political implications of recent policy shifts. FDA Deputy Commissioner for Food Kyle Diamantas will lead the agency as acting commissioner until a replacement is confirmed. The dietary supplement industry is closely monitoring the situation to see if the next nominee will sustain the MAHA-aligned policy or revert to more conventional regulatory norms. The Consumer Healthcare Products Association (CHPA) emphasized the need for regulatory stability and continuity to protect public health and enable industry innovation. Nutritional Outlook
Unilever Acquires Grüns in $1.2 Billion Deal
Unilever has signed an agreement to acquire Grüns, a fast-growing US greens supplement brand known for its gummy products. The acquisition, reportedly valued at $1.2 billion, marks Unilever's continued shift toward premium health and wellness brands. Grüns has successfully built a trusted brand with retail placement and a growing product line, making it an attractive target for Unilever's expansion in the functional nutrition space. Nutraceutical Business Review
Function Health Acquires Supplement Watchdog SuppCo
Digital health platform Function Health has acquired SuppCo, an independent testing platform and app that serves as a consumer watchdog for the supplement industry. SuppCo has tested and rated thousands of products for quality and label accuracy, recently finding that many popular supplements fail to meet their label claims. The acquisition aims to combine biological data tracking with vetted supplements to improve health outcomes, connecting supplement stacks to real lab data. Athletech News
Business & Investment
TopGum Completes US Acquisition of PL Developments
TopGum Industries Ltd. has completed the acquisition of P&L Developments LLC's US gummy manufacturing operations for $35 million. This acquisition provides TopGum with a US-based manufacturing platform built to FDA pharmaceutical standards, capable of producing both pharmaceutical gummies and dietary supplements. The strategic move positions TopGum to serve large dietary supplement brands in the US with local manufacturing. FNB News
MANE Group Acquires FROMATECH Ingredients
MANE Group has acquired Dutch savoury flavour specialist FROMATECH Ingredients B.V. to strengthen its presence in high-growth markets, particularly the MENA region. The acquisition aligns with MANE's growth strategy and follows its recent purchase of Chemosensoryx Biosciences. Nutraceutical Business Review
Science & Research
Eneboparatide Normalizes Serum Calcium in Hypoparathyroidism Trial
Positive results from the CALYPSO Phase III trial showed that eneboparatide met its composite primary endpoint in adults with chronic hypoparathyroidism. The treatment demonstrated a statistically significant normalization of serum calcium levels and independence from active vitamin D and oral calcium supplements in 31.1% of adults at week 24. These late-breaking results were presented at the European Congress of Endocrinology. AstraZeneca
Diet Change Reverses Biological Age in Older Adults
A four-week diet change was enough to make some older adults appear biologically younger in a new University of Sydney study. Participants who reduced fat intake or shifted toward more plant-based protein showed improvements in key health biomarkers tied to aging. The strongest results came from a lower-fat, higher-carb diet. For those looking to support their foundational health alongside dietary changes, incorporating a high-quality Vitamin B-Complex can help maintain optimal energy metabolism and cellular function as we age. ScienceDaily
New Product Launches & Formulation
AG1 Debuts at Ulta Beauty
AG1 has launched at Ulta Beauty, marking its first partnership with a beauty retailer. The launch features 7-count and 14-count packs of both AG1 and AGZ, as well as the AG1 Start Here Kit. This move reflects growing consumer demand for holistic wellness solutions that support beauty from within and offers a more flexible way for consumers to try the product without committing to a full monthly supply. Nutraceuticals World
Cosmax NBT Introduces High-Capacity Jelly Stick Format
Cosmax NBT has launched functional jelly stick packs, a single-serve delivery system designed for ingredient stability, dosing precision, and low-sugar formulations. The jelly stick serving size ranges from 25 to 30 grams, providing nearly ten times the space for meaningful doses of functional ingredients compared to standard gummies. This format is positioned as a versatile solution for various health categories, including beauty-from-within, energy and sports nutrition, gut health and immunity, and women's health. For those focused on comprehensive digestive support, a robust Multispore Probiotic remains a cornerstone of any effective gut health regimen. Nutritional Outlook
Nature's Bounty Introduces Skin Renewal Supplement
Nature's Bounty has introduced Age-Defying Skin Renewal, a dietary supplement that targets five key signs of aging, including fine lines and wrinkles. The launch aligns with the growing trend of beauty-from-within supplements and consumer interest in proactive skin health management. Nutraceuticals World
Regulations & Quality
CRN Responds to Criticism of DSHEA
The Council for Responsible Nutrition's Steve Mister responded to criticism of DSHEA, explaining that issues with "gas station drugs" highlight enforcement gaps rather than a lack of regulation. He emphasized that legitimate dietary supplement companies operate under a comprehensive federal regulatory framework. Mister also renewed calls for a mandatory dietary supplement product registry to help the FDA identify and remove illegitimate products from the market. WholeFoods Magazine
Heavy Metals in the Pet Supplement Supply Chain
Heavy metals enter the pet food supplement supply chain through natural mineral contamination of raw ingredients like soil, water, and plant material. Without robust ingredient specification and testing, these contaminants pass straight through into the finished product. This highlights the critical need for stringent quality control and testing standards across all supplement categories. All Pet Food
Marketing & Consumer Trends
U.S. News OTC Report Highlights Precision Supplementation
The 2026 U.S. News OTC Report reveals 11 new categories in nutritional supplements, tapping into growing demand for specialized health products. The report highlights the shift toward precision supplementation and life-stage-focused wellness, with consumers seeking targeted solutions for performance and longevity. New categories include Collagen Peptides, Creatine, Digestive Enzymes, Fertility Support, Menopause Supplements, and Natural Sleep Aids. For those seeking targeted support for relaxation and nervous system health, highly bioavailable forms like Magnesium Glycinate continue to be top recommendations among health professionals. NutritionInsight
Vitafoods Europe 2026 Spotlights Longevity and Women's Health
At the recent Vitafoods Europe 2026 trade show, longevity, women's health, delivery formats, the gut microbiome, and metabolic wellness took center stage. Longevity supplements are becoming a younger, proactive trend, with consumers seeking science-backed, enjoyable formats that integrate into daily routines. Companies showcased new ingredients and consumer-centric formats, such as Sirio's Aeion longevity platform featuring LifeChews, FizzyBits, and SnowMelt formats. NutritionInsight
BODi Enters Brick-and-Mortar Retail
BODi is launching its Shakeology nutrition line in Sprouts Farmers Market and The Vitamin Shoppe, marking its first brick-and-mortar retail partnerships. The company also partnered with KeHE for broader distribution across grocery and specialty retailers. This move follows BODi's transition away from its multi-level marketing model and expands its reach to consumers seeking convenient nutrition options in traditional retail settings. Athletech News